大容量复方微乳联合微针导入对改善黄褐斑治疗的临床效果

摘要:

探讨大容量复方微乳联合微针导入治疗黄褐斑的临床效果。方法 选取2022年1月-7月于海 口红妆尚医学美容医院、柳州美嘉医疗美容诊所、广州紫馨整形外科医院治疗的60例黄褐斑患者为研究对 象，随机分为对照组和观察组，每组30例。对照组使用5 ml微乳联合微针导入治疗，观察组使用55 ml微 乳联合微针导入治疗，比较两组临床疗效、MASI评分、不良反应发生情况。结果 观察组治疗总有效率为 93.33%，高于对照组的70.00%，差异有统计学意义（P ＜0.05）；观察组治疗1、3、6个月的MASI评分低于 对照组，差异有统计学意义（P ＜0.05）；两组面部疼痛、红肿、瘙痒、色素沉着加重等不良反应发生率比 较，差异无统计学意义（P ＞0.05）。结论 大容量复方微乳联合微针导入治疗黄褐斑的临床疗效理想，能 有效淡化斑块，改善肤质，提高皮肤白皙度，且不良反应发生率较低，临床疗效及安全性较好。

关键词:黄褐斑;微针导入;复方微乳;大容量

Abstract:

To investigate the clinical effect of large-capacity compound microemulsion combined with microneedle introduction in the treatment of chloasma. Methods A total of 60 patients with chloasma who were treated in Haikou Red Fashion Medical Cosmetic Hospital, Liuzhou Meijia Medical Cosmetology Clinic and Guangzhou Zixin Plastic Surgery Hospital from January to July 2022 were randomly divided into control group and observation group, with 30 patients in each group. The control group was treated with 5 ml microemulsion combined with microneedle introduction, and the observation group was treated with 55 ml microemulsion combined with microneedle introduction. The clinical efficacy, MASI score and adverse reactions were compared between the two groups. Results The total effective rate of treatment in the observation group was 93.33%, which was higher than 70.00% in the control group, and the difference was statistically significant (P <0.05). The MASI scores of the observation group at 1,3 and 6 months after treatment were lower than those of the control group, and the differences were statistically significant (P <0.05). There was no significant difference in the incidence of adverse reactions such as facial pain, redness, itching, and increased pigmentation between the two groups (P >0.05). Conclusion The clinical efficacy of large-capacity compound microemulsion combined with microneedle introduction in the treatment of chloasma is ideal, which can effectively dilute plaque, improve skin quality, improve skin whiteness, and the incidence of adverse reactions is low . The clinical efficacy and safety are good.

Key words:Chloasma; Microneedle introduction; Compound microemulsion; Large-capacity